🧠 Does Your Brain Need High Cholesterol to Function? 🩺 A recent study published in NEJM Evidence investigated the long-term cognitive effects of achieving very low levels of low-density lipoprotein (LDL) cholesterol using evolocumab, a PCSK9 inhibitor. Participants, already on statin therapy, were assessed over a median of 5.1 years. The findings revealed no significant impact on cognitive function over time, suggesting that intensive LDL cholesterol reduction is safe for both heart and brain